Phenotypes Associated with This Genotype

Genotype
MGI:3703442

• Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

craniofacial phenotype ( J:81179 )

N • at E9.5, no defects are seen in the early development of the second branchial arch unlike mice homozygous for Fgfr1^tm2Jrt

N • also, the malleus, incus, stapes, styloid process, tympanic ring, alisphenoid and squamosum are normal

abnormal hyoid bone lesser horn morphology ( J:81179 )

• lesser horn points laterally

cleft palate ( J:81179 )

• in newborns

digestive/alimentary system

cleft palate ( J:81179 )

• in newborns

skeleton

abnormal hyoid bone lesser horn morphology ( J:81179 )

• lesser horn points laterally

growth/size/body

abnormal hyoid bone lesser horn morphology ( J:81179 )

• lesser horn points laterally

cleft palate ( J:81179 )

• in newborns