Phenotypes Associated with This Genotype

Genotype
MGI:3702091

• Allelic Composition: Cd19^tm1(cre)Cgn/Cd19⁺; Pdia3^tm1Gjh/Pdia3^tm1Gjh
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal B cell physiology ( J:112606 )

• naive B cells express 50% - 90% less H-2K^b and have decreased H-2D^b expression

• however, B cell development, survival, and proliferative responses are similar to control mice and mice raise normal titers of IgG

hematopoietic system

abnormal B cell physiology ( J:112606 )

• naive B cells express 50% - 90% less H-2K^b and have decreased H-2D^b expression

• however, B cell development, survival, and proliferative responses are similar to control mice and mice raise normal titers of IgG