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Phenotypes Associated with This Genotype
Genotype
MGI:3701599
Allelic
Composition		 Cdh23ahl/Cdh23ahl
Adgrv1frings/Adgrv1frings
Genetic
Background		 involves: BUB/BnJ * RB/1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrv1frings mutation (1 available); any Adgrv1 mutation (318 available)
Cdh23ahl mutation (51 available); any Cdh23 mutation (274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased susceptibility to age-related hearing loss ( J:97534 )
• exhibit the highest ABR threshold compared to single homozygous mice Gpr98frings/Gpr98frings Cdh23ahl/Cdh23+ and Gpr98frings/Gpr98+ Cdh23ahl/Cdh23ahl
deafness ( J:97534 )
• already near deaf by 5 months of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory