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Phenotypes Associated with This Genotype
Genotype
MGI:3698865
Allelic
Composition		 Sin3atm1.1Rdp/Sin3a+
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sin3atm1.1Rdp mutation (0 available); any Sin3a mutation (60 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (249 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:117829 )
N
• mice show identical tumor incidence, tumor multiplicity, and tumor spectrum to mice with a Sin3a-sufficient, Trp53-null background

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory