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Phenotypes Associated with This Genotype
Genotype
MGI:3698747
Allelic
Composition		 Zap70m1Saka/Zap70tm1Dlo
Tg(Lck-ZAP70)824Saka/0
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Lck-ZAP70)824Saka mutation (0 available)
Zap70m1Saka mutation (1 available); any Zap70 mutation (53 available)
Zap70tm1Dlo mutation (0 available); any Zap70 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:86607 )
• expression of transgene completely inhibits development of arthritis and corrects immunological abnormalities observed in Zap70-deficient mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory