Phenotypes Associated with This Genotype

Genotype
MGI:3697586

• Allelic Composition: Cr1l^tm1Hmo/Cr1l⁺
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased blood urea nitrogen level ( J:105466 )

• significantly elevated serum urea nitrogen following 20 minutes of bilateral renal ischemia and 24 hours of reperfusion

increased susceptibility to kidney reperfusion injury ( J:105466 )

• significantly greater injury following 20 minutes of bilateral renal ischemia and 24 hours of reperfusion particularly in the proximal tubules

renal/urinary system

increased susceptibility to kidney reperfusion injury ( J:105466 )

• significantly greater injury following 20 minutes of bilateral renal ischemia and 24 hours of reperfusion particularly in the proximal tubules

abnormal proximal convoluted tubule morphology ( J:105466 )

• significantly greater injury following 20 minutes of bilateral renal ischemia and 24 hours of reperfusion particularly in the proximal tubules