Phenotypes Associated with This Genotype

Genotype
MGI:3697240

• Allelic Composition: Ephb2^tm1Jf/Ephb2^tm1Jf
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal crypts of Lieberkuhn morphology ( J:115873 )

• a 19% and 30% increase in the number of proliferating cells is detected in crypts in the small intestine and colon, respectively

• however, no signs of cell migration defects are seen in the intestinal epithelium

endocrine/exocrine glands

abnormal crypts of Lieberkuhn morphology ( J:115873 )

• a 19% and 30% increase in the number of proliferating cells is detected in crypts in the small intestine and colon, respectively

• however, no signs of cell migration defects are seen in the intestinal epithelium

nervous system

abnormal axon morphology ( J:176056 )

• some mice exhibit ventral-temporal (VT) retinal ganglion cell axon mapping defects compared with control mice