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Phenotypes Associated with This Genotype
Genotype
MGI:3693491
Allelic
Composition
Tg(PSEN1H163R)G9Btla/0
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PSEN1H163R)G9Btla mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• lower levels of Abeta1-42 amyloid peptide accumulate compared to double transgenic mice

homeostasis/metabolism
• lower levels of Abeta1-42 amyloid peptide accumulate compared to double transgenic mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Alzheimer's disease DOID:10652 J:58050
Alzheimer's disease 3 DOID:0110042 OMIM:607822
J:58050


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory