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Phenotypes Associated with This Genotype
Genotype
MGI:3693490
Allelic
Composition		 Tg(APPSw)40Btla/Tg(APPSw)40Btla
Tg(PSEN1H163R)G9Btla/0
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APPSw)40Btla mutation (4 available)
Tg(PSEN1H163R)G9Btla mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:58050 )
• mice develop extensive amyloid beta fibrillar deposits in brain by 7 months

homeostasis/metabolism
amyloid beta deposits ( J:58050 )
• mice develop extensive amyloid beta fibrillar deposits in brain by 7 months

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory