Phenotypes for Fas Tg(Mx1-cre)1Cgn MGI:3690550 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fas^tm1Cgn/Fas^tm1Cgn Tg(Mx1-cre)1Cgn/0
Genetic Background	B6.Cg-Fas^tm1Cgn Tg(Mx1-cre)1Cgn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fas^tm1Cgn mutation (1 available); any Fas mutation (83 available)
Tg(Mx1-cre)1Cgn mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immune system morphology ( J:114948 )

• after Poly(I) Poly(C) induction of cre expression mice develop the lymphoproliferative disease seen in Fas^tm1.1Cgn homozygtes

enlarged spleen ( J:114948 )

enlarged lymph nodes ( J:114948 )

hematopoietic system

enlarged spleen ( J:114948 )

growth/size/body

enlarged spleen ( J:114948 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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