Analysis Tools
cellular
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• when stimulated with anti-CD3 antibodies or engagement of CD3 and CD28 receptors, T cell proliferation is impaired compared to in similarly treated wild-type cells
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immune system
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• Staphylococcal enterotoxin B-induced deletion of single positive T cells is less than in wild-type mice
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• when stimulate by anti-CD3 and anti-CD3 and anti-CD28 antibodies, CD4+ T cells exhibit reduced blast population compared with similarly treated wild-type cells
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• when stimulated with anti-CD3 antibodies or engagement of CD3 and CD28 receptors, T cell proliferation is impaired compared to in similarly treated wild-type cells
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• T cells stimulated with anti-CD3 and anti-CD28 antibodies produce less IL2 than similarly treated wild-type or Rasgrf2tm1Esn cells
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• T cells stimulated with anti-CD3 or anti-CD3 and anti-CD28 antibodies produce less TNF-alpha than similarly treated wild-type or Rasgrf2tm1Esn cells
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hematopoietic system
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• Staphylococcal enterotoxin B-induced deletion of single positive T cells is less than in wild-type mice
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• when stimulate by anti-CD3 and anti-CD3 and anti-CD28 antibodies, CD4+ T cells exhibit reduced blast population compared with similarly treated wild-type cells
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• when stimulated with anti-CD3 antibodies or engagement of CD3 and CD28 receptors, T cell proliferation is impaired compared to in similarly treated wild-type cells
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