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Phenotypes Associated with This Genotype
Genotype
MGI:3688533
Allelic
Composition
FlnaDilp2/Y
Genetic
Background
involves: BALB/cAnN * C3H/HeN * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
FlnaDilp2 mutation (2 available); any Flna mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• die by E15.5 (J:112274)
• die by E15.5 (J:112274)

cardiovascular system
• outflow tract seems to be more centrally located and fails to separate (J:112274)
• outflow tract seems to be more centrally located and fails to separate (J:112274)
• exhibit a common arterial trunk in which there is no separate aorta and pulmonary artery, but a single vessel that emerges from the right ventricle (J:112274)
• exhibit a common arterial trunk in which there is no separate aorta and pulmonary artery, but a single vessel that emerges from the right ventricle (J:112274)
(J:112274)
(J:112274)
• exhibit thickening of the mitral valve (dysplasia) (J:112274)
• exhibit thickening of the mitral valve (dysplasia) (J:112274)
• exhibit atrial septal defect primum (J:112274)
• exhibit atrial septal defect primum (J:112274)
• exhibit ventricular septal defects (J:112274)
• exhibit ventricular septal defects (J:112274)

craniofacial
(J:112274)
(J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)

homeostasis/metabolism
(J:112274)
(J:112274)

skeleton
• exhibit incomplete fusion of the sternum at E15.5 (J:112274)
• exhibit incomplete fusion of the sternum at E15.5 (J:112274)

digestive/alimentary system
(J:112274)
(J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)

growth/size/body
(J:112274)
(J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)
• palatal shelves fail to elevate at E15.5 (J:112274)
• exhibit umbilical hernia and show delayed resorption of the hernia (J:112274)
• exhibit umbilical hernia and show delayed resorption of the hernia (J:112274)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory