Mouse Genome Informatics
ot
    FlnaDilp2/Y
involves: BALB/cAnN * C3H/HeN * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• outflow tract seems to be more centrally located and fails to separate
• exhibit a common arterial trunk in which there is no separate aorta and pulmonary artery, but a single vessel that emerges from the right ventricle
• exhibit thickening of the mitral valve (dysplasia)
• exhibit atrial septal defect primum
• exhibit ventricular septal defects

craniofacial
• palatal shelves fail to elevate at E15.5

homeostasis/metabolism

skeleton
• exhibit incomplete fusion of the sternum at E15.5

digestive/alimentary system
• palatal shelves fail to elevate at E15.5

growth/size/body
• palatal shelves fail to elevate at E15.5
• exhibit umbilical hernia and show delayed resorption of the hernia

Mouse Models of Human Disease
OMIM IDRef(s)
Heterotopia, Periventricular, X-Linked Dominant 300049 J:112274
Melnick-Needles Syndrome; MNS 309350 J:112274
Otopalatodigital Syndrome, Type I; OPD1 311300 J:112274
Otopalatodigital Syndrome, Type II; OPD2 304120 J:112274