About   Help   FAQ
FlnaDilp2
Chemically induced Allele Detail
Summary
Symbol: FlnaDilp2
Name: filamin, alpha; dilated pupils 2
MGI ID: MGI:1934627
Synonyms: Gena379, GENA 379
Gene: Flna  Location: ChrX:73267067-73293426 bp, - strand  Genetic Position: ChrX, 37.89 cM
Alliance: FlnaDilp2 page
Mutation
origin
Strain of Origin:  (C3H/HeN x BALB/cAnN)F1
Project Collection: Harwell ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis phenotypic mutant was identified in an ENU mutagenesis screen at Harwell. A single T to A transversion is found in exon 44 at position 7164. This converts a tyrosine codon to a nonsense codon at position 2388 in the protein. (J:112274)
Inheritance:    Semidominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 20 assay results
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Flna Mutation:  18 strains or lines available
References
Original:  J:75964 Thaung C, et al., Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet. 2002 Apr 1;11(7):755-67
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory