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Phenotypes Associated with This Genotype
Genotype
MGI:3688511
Allelic
Composition		 Slc16a2tm1.1Sref/Slc16a2tm1.1Sref
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc16a2tm1.1Sref mutation (1 available); any Slc16a2 mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal circulating hormone level ( J:113732 )
• serum levels of rT3 (reverse T3, competitive inhibitor of T3) are lower than in heterozygous littermates
decreased circulating thyroxine level ( J:113732 )
• T4 serum levels are lower than female heterozygous littermates
increased triiodothyronine level ( J:113732 )
• mutants have higher serum T3 levels than female heterozygous littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory