Phenotypes Associated with This Genotype

Genotype
MGI:3688304

• Allelic Composition: Srebf1^tm1Mbr/Srebf1^tm1Mbr
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating cholesterol level ( J:75320 )

• the level of plasma cholesterol was significantly reduced in 8-10 weeks old male mice on normal diet

decreased circulating triglyceride level ( J:75320 )

• the level of plasma triglyceride was significantly reduced in 8-10 weeks old male mice on normal diet

increased liver cholesterol level ( J:75320 )

• the liver cholesterol content was significantly increased in 8-10 weeks old male mice on normal diet

liver/biliary system

increased liver cholesterol level ( J:75320 )

• the liver cholesterol content was significantly increased in 8-10 weeks old male mice on normal diet