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Phenotypes Associated with This Genotype
Genotype
MGI:3687168
Allelic
Composition		 Rag1tm1Mom/Rag1tm1Mom
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1tm1Mom mutation (56 available); any Rag1 mutation (132 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
small thymus ( J:111874 )
• nontransgenic Rag1 homozygotes have extremely small thymi
decreased lymphocyte cell number ( J:111874 )
• non-transgenic Rag1-null mice display lymphopenia more severe than transgenic Rag1-null mice

immune system
small thymus ( J:111874 )
• nontransgenic Rag1 homozygotes have extremely small thymi
decreased lymphocyte cell number ( J:111874 )
• non-transgenic Rag1-null mice display lymphopenia more severe than transgenic Rag1-null mice

endocrine/exocrine glands
small thymus ( J:111874 )
• nontransgenic Rag1 homozygotes have extremely small thymi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory