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Phenotypes Associated with This Genotype
Genotype
MGI:3663589
Allelic
Composition
Axin1Fu-ki/Axin1+
Genetic
Background
mixed
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Axin1Fu-ki mutation (0 available); any Axin1 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• some vertebrae show abnormalities in structure, with one side shorter than the other, causing the following vertebra to form an angle with it
• two neighboring vertebrae may be fused, producing stiff tail segments
• may be reduced to as little as 1/2 of normal length
• occasionally observe bifurcations of the tail
• variable tail flexure, ranging from a barely perceptible bend or bump to a strong spiral twist

skeleton
• partial and total rib fusions due to reductions of vertebrae
• some vertebrae show abnormalities in structure, with one side shorter than the other, causing the following vertebra to form an angle with it
• two neighboring vertebrae may be fused, producing stiff tail segments
• abnormalities include eccentric reductions of single vertebrae
• ankyloses between adjacent vertebrae
• abnormalities include eccentric reductions of single vertebrae
• ankyloses between adjacent vertebrae
• abnormalities include eccentric reductions of single vertebrae
• ankyloses between adjacent vertebrae


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory