Phenotypes Associated with This Genotype

Genotype
MGI:3663274

• Allelic Composition: \Otx2^tm1Sla/\Otx2^tm1Sla
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal rostral-caudal axis patterning ( J:74124 )

• A-P axis appears to be aligned incorrectly and the anterior pole of the axis remains in the distal region of the embryo

abnormal primitive streak formation ( J:74124 )

• the streak is incorrectly positioned in the proximal region of the epiblast

abnormal primitive streak elongation ( J:74124 )

• primitive streak does not extend the full length of the posterior side of the embryo