Mouse Genome Informatics
cn
    Rettm1Kln/Rettm1Kln
Tg(Nes-cre)1Kln/0

involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• mutants have peroneal nerves (PN) of reduced length (~40% of control) at E11.5 and nerves are reduced in complexity at E12.5; diameter of peroneal nerve is also reduced
• phenotype at E12.5 is somewhat less severe than in Ret; Tg(Pgk1-cre)1Lni mice

limbs/digits/tail
• clubbed feet are observed in mutants after birth

Mouse Models of Human Disease
OMIM IDRef(s)
Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF 119800 J:110955