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Phenotypes Associated with This Genotype
Genotype
MGI:3662906
Allelic
Composition
Rettm1Kln/Rettm1Kln
Tg(Nes-cre)1Kln/0
Genetic
Background
involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rettm1Kln mutation (0 available); any Ret mutation (22 available)
Tg(Nes-cre)1Kln mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants have peroneal nerves (PN) of reduced length (~40% of control) at E11.5 and nerves are reduced in complexity at E12.5; diameter of peroneal nerve is also reduced
• phenotype at E12.5 is somewhat less severe than in Ret; Tg(Pgk1-cre)1Lni mice

limbs/digits/tail
• clubbed feet are observed in mutants after birth


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory