Phenotypes Associated with This Genotype

Genotype
MGI:3653639

• Allelic Composition: Kl^kl/Kl^kl; Tnfrsf11b^tm1Khs/Tnfrsf11b⁺
• Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

short femur ( J:80503 )

• femur length is shorter than in mice homozygous for Kl only; however osteopetrotic changes in the bone are reduced and the number of osteoclasts is similar to wild-type

growth/size/body

decreased body weight ( J:80503 )

• similar to mice homozygous for Kl mutation only

immune system

decreased B cell number ( J:80503 )

• similar to mice homozygous for Kl mutation only

limbs/digits/tail

short femur ( J:80503 )

• femur length is shorter than in mice homozygous for Kl only; however osteopetrotic changes in the bone are reduced and the number of osteoclasts is similar to wild-type

hematopoietic system

decreased B cell number ( J:80503 )

• similar to mice homozygous for Kl mutation only