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Phenotypes Associated with This Genotype
Genotype
MGI:3652904
Allelic
Composition		 Gja1tm1Gfi/Gja1tm1Gfi
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129/Sv * C57BL/6J * CBA/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1tm1Gfi mutation (0 available); any Gja1 mutation (62 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal ascending aorta and coronary artery attachment ( J:108525 )
• 3 of 5 mutants exhibit coronary abnormalities that include separate ostia for right septal and myocardial coronary tributaries, accessory coronary artery originating from the non-coronary sinus, or tunneling of the left coronary artery through the wall of the aorta, however do not exhibit outflow tract defects

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory