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Phenotypes Associated with This Genotype
Genotype
MGI:3641106
Allelic
Composition		 Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(GFAP-cre)25Mes/0
Genetic
Background		 involves: 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm1Upir mutation (0 available); any Fgfr1 mutation (218 available)
Fgfr2tm1Dor mutation (3 available); any Fgfr2 mutation (88 available)
Tg(GFAP-cre)25Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal astrocyte morphology ( J:110263 )
• numbers of astrocytes reaching the cortex is significantly reduced compared to controls at P7

cellular
abnormal astrocyte morphology ( J:110263 )
• numbers of astrocytes reaching the cortex is significantly reduced compared to controls at P7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory