About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3641106
Allelic
Composition		 Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(GFAP-cre)25Mes/0
Genetic
Background		 involves: 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm1Upir mutation (0 available); any Fgfr1 mutation (219 available)
Fgfr2tm1Dor mutation (3 available); any Fgfr2 mutation (91 available)
Tg(GFAP-cre)25Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal astrocyte morphology ( J:110263 )
• numbers of astrocytes reaching the cortex is significantly reduced compared to controls at P7

cellular
abnormal astrocyte morphology ( J:110263 )
• numbers of astrocytes reaching the cortex is significantly reduced compared to controls at P7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory