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Phenotypes Associated with This Genotype
Genotype
MGI:3641104
Allelic
Composition
Fgfr1tm1Upir/Fgfr1tm1Upir
Tg(Nes-cre)1Kln/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm1Upir mutation (0 available); any Fgfr1 mutation (221 available)
Tg(Nes-cre)1Kln mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice have defects in the dorsal telencephalic commissures
• all mutants have a complete absence of midline crossing at the most anterior and posterior region
• about 20% of mice have a small number of callosal fibers in the region above the hippocampal commissure
• axons are absent in the contralateral cortex or white matter
• the cortical fibers are trapped within Probst bundles


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory