Phenotypes Associated with This Genotype

Genotype
MGI:3640211

• Allelic Composition: Fgfr3^tm4.1Cxd/Fgfr3⁺
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:70061 )

• lethality at birth

craniofacial

round head ( J:70061 )

• round head

limbs/digits/tail

bowed ulna ( J:70061 )

• marked bowing of the ulna

bowed tibia ( J:70061 )

• marked bowing of the tibia

short limbs ( J:70061 )

• shorter limbs with particularly shortened ossified zone

skeleton

bowed ulna ( J:70061 )

• marked bowing of the ulna

bowed tibia ( J:70061 )

• marked bowing of the tibia

increased diameter of long bones ( J:70061 )

• widening of limb long bones

abnormal spine curvature ( J:70061 )

• exhibit curvature of the axial skeleton

growth/size/body

round head ( J:70061 )

• round head