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Phenotypes Associated with This Genotype
Genotype
MGI:3639683
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19+
Cxcr4tm1Tng/Cxcr4tm2Tng
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Cxcr4tm1Tng mutation (1 available); any Cxcr4 mutation (50 available)
Cxcr4tm2Tng mutation (1 available); any Cxcr4 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased plasma cell number ( J:109147 )
• the number of plasma cells in bone marrow were severely reduced
• the numbers of mature B cells and plasma cells in spleen were normal

immune system
decreased plasma cell number ( J:109147 )
• the number of plasma cells in bone marrow were severely reduced
• the numbers of mature B cells and plasma cells in spleen were normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory