Analysis Tools
mortality/aging
|
• all die by 3.5 months of pituitary tumors
|
growth/size/body
weight loss
(
J:50053
)
|
• appear thin by 3 months of age
|
behavior/neurological
homeostasis/metabolism
dehydration
(
J:50053
)
|
• appear dehydrated by 3 months of age
|
neoplasm
|
• develop pituitary tumors (by 3 months of age) at an accelerated rate compared to the single homozygous mice
|
|
• one mutant developed a pituitary carcinoma
|
cardiovascular system
endocrine/exocrine glands
|
• pituitary glands are larger than in single homozygous mutants
|
|
• lobe is hyperplastic
|
|
• develop pituitary tumors (by 3 months of age) at an accelerated rate compared to the single homozygous mice
|
hematopoietic system
reproductive system
nervous system
|
• pituitary glands are larger than in single homozygous mutants
|
|
• lobe is hyperplastic
|
|
• develop pituitary tumors (by 3 months of age) at an accelerated rate compared to the single homozygous mice
|
immune system
