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Phenotypes Associated with This Genotype
Genotype
MGI:3639582
Allelic
Composition
Itgb1tm3Mlkn/Itgb1tm3Mlkn
Tg(Mx1-cre)1Cgn/0
Genetic
Background
involves: 129/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm3Mlkn mutation (0 available); any Itgb1 mutation (58 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• after ADP stimulation, platelets fail to bind soluble collagen in an inside-out activation assay
• severely defective platelet adhesion to collagen under flow is observed in mutants in an outside-in activation assay


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory