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Phenotypes Associated with This Genotype
Genotype
MGI:3639308
Allelic
Composition		 Grik1tm1Sfh/Grik1tm1Sfh
Grik2tm1Sfh/Grik2tm1Sfh
Genetic
Background		 involves: 129S/SvEv * 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grik1tm1Sfh mutation (0 available); any Grik1 mutation (51 available)
Grik2tm1Sfh mutation (0 available); any Grik2 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal inhibitory postsynaptic currents ( J:66021 )
• spontaneous IPSC frequency increases after domoate stimulation is completely eliminated in CA1 pyramidal neurons
• evoked IPSC is eliminated

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory