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Phenotypes Associated with This Genotype
Genotype
MGI:3630273
Allelic
Composition		 Cd8atm1Mak/Cd8atm1Mak
Irf2tm1Mak/Irf2tm1Mak
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8atm1Mak mutation (7 available); any Cd8a mutation (37 available)
Irf2tm1Mak mutation (1 available); any Irf2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal skin condition ( J:66034 )
• no skin symptoms are observed up to 4 months of age compared to Irf2-null mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory