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Phenotypes Associated with This Genotype
Genotype
MGI:3629946
Allelic
Composition		 Grm2tm1Nak/Grm2tm1Nak
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm2tm1Nak mutation (1 available); any Grm2 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal excitatory postsynaptic potential ( J:34606 )
• slight variations are seen in the time course of fEPSP in CA3 as a result of mossy fiber stimulation
reduced long-term depression ( J:34606 )
• impaired LTD at mossy fiber-CA3 synapses

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/16/2026
MGI 6.24 		The Jackson Laboratory