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Phenotypes Associated with This Genotype
Genotype
MGI:3629523
Allelic
Composition		 Tcrdtm1Mom/Tcrdtm1Mom
Tnftm2Gkl/Tnf+
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcrdtm1Mom mutation (13 available); any Tcrd mutation (15 available)
Tnftm2Gkl mutation (1 available); any Tnf mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
small intestinal inflammation ( J:108572 )
• development and severity of inflammatory bowel disease are similar to Tnftm2Gkl/+, wild-type B2m controls

digestive/alimentary system
small intestinal inflammation ( J:108572 )
• development and severity of inflammatory bowel disease are similar to Tnftm2Gkl/+, wild-type B2m controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory