Phenotypes Associated with This Genotype

Genotype
MGI:3624750

• Allelic Composition: Zeb2^tm1.1Yhi/Zeb2^tm1.1Yhi; Tg(Pax6-cre,GFP)1Pgr/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:101730 )

• exhibit a persistent lens stalk at E13.5, E14.5 and even P0

abnormal lens fiber morphology ( J:101730 )

• arrest of lens fiber cell maturation at the bow-region stage

small lens ( J:101730 )

• increase in apoptotic cells in the lens results in a smaller lens size