About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3624416
Allelic
Composition
Psen1tm1Zhe/Psen1tm1Zhe
Tg(APPSWE)2576Kha/?
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psen1tm1Zhe mutation (0 available); any Psen1 mutation (28 available)
Tg(APPSWE)2576Kha mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• dramatically higher plaque density in brain compared to control Tg(APPSWE)2576Kahs transgenic mice
• numerous plaques could be detected in both the cortex and hippocampus at 10 month

homeostasis/metabolism
• dramatically higher plaque density in brain compared to control Tg(APPSWE)2576Kahs transgenic mice
• numerous plaques could be detected in both the cortex and hippocampus at 10 month

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:107251


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/26/2016
MGI 6.03
The Jackson Laboratory