Phenotypes Associated with This Genotype

Genotype
MGI:3623729

• Allelic Composition: Lrp4^mdig/Lrp4^mdig
• Genetic Background: involves: 129S2/SvPas * DBA/1LacJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

brachydactyly ( J:108168 )

• variable brachydactyly seen on all four limbs

polydactyly ( J:108168 )

• duplication of digits along the dorsoventral axis

syndactyly ( J:108168 )

• variable syndactyly seen on all four limbs

• typically involves fusion of 2 or 3 adjacent segments along the anteroposterior axis

polysyndactyly ( J:108168 )

behavior/neurological

abnormal nursing ( J:108168 )

♀ • females and males are fertile but females sometimes fail to nurse their pups

craniofacial

craniofacial phenotype ( J:108168 )

N • no tooth abnormalities are seen

integument

deformed nails ( J:108168 )

• nails are often abnormally shaped or placed but are never fused