Mouse Genome Informatics
cn
    Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Ckmm-cre)5Khn/?

involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
muscle
• increase in muscle damage following exercise

homeostasis/metabolism
• increased serum levels of the MM isoform of creatine kinase 1 day after exercise
• significant decrease in lactate accumulation after exercise
• increased endurance in swim tests and in the first session of running uphill (concentric exercise) but decreased endurance when running downhill (eccentric exercise)
• endurance decreased over 4 consecutive days of daily treadmill running

nervous system
• slight but statistically significant decrease in type IIa fibers in the soleus

Mouse Models of Human Disease
OMIM IDRef(s)
Glycogen Storage Disease V 232600 J:97761
Glycogen Storage Disease VII 232800 J:97761