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Phenotypes Associated with This Genotype
Genotype
MGI:3619337
Allelic
Composition
Agtr1atm1Unc/Agtr1atm1Unc
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtr1atm1Unc mutation (1 available); any Agtr1a mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• loss of pressure responses to angiotensin II administration
• arterial pressure measured by carotid cannula is reduced by 43 mmHg, however homozygotes appear to have a normal heart, kidney and vascular system
• systolic blood pressure measured by tail cuff sphygmomanometer is reduced by 24 mmHg


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory