Phenotypes Associated with This Genotype

Genotype
MGI:3617776

• Allelic Composition: Met^tm1Cbm/Met^tm1Cbm
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

decreased trophoblast giant cell number ( J:68751 )

• at E13.5

abnormal placenta labyrinth morphology ( J:68751 )

• at E13.5, the labyrinth layer is disorganized and reduced in thickness; however the spongiotrophoblast layer is similar to wild-type

liver/biliary system

decreased liver weight ( J:68751 )

• at E14.5, the liver to body weight ratio is significantly reduced (0.053 versus 0.106 in wild-type)