Phenotypes for Gli3 Glis1 MGI:3615815 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gli3^Xt/Gli3^Xt Glis1^tm1Mnks/Glis1^tm1Mnks
Genetic Background	mixed

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli3^Xt mutation (1 available); any Gli3 mutation (84 available)
Glis1^tm1Mnks mutation (0 available); any Glis1 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

polydactyly ( J:80052 )

• similar to Gli3^xt homozygous mutant mice

nervous system

abnormal brain morphology ( J:80052 )

• embryonic dorsal brain defects are similar to Gli3^xt homozygous mutant embryos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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