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Phenotypes Associated with This Genotype
Genotype
MGI:3615451
Allelic
Composition		 Cbfbtm1Lhc/Cbfb+
Tg(EIIa-cre)C5379Lmgd/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbfbtm1Lhc mutation (0 available); any Cbfb mutation (39 available)
Tg(EIIa-cre)C5379Lmgd mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:105040 )
• embryos die by midgestation

hematopoietic system
impaired hematopoiesis ( J:105040 )
• embryos display hematopoeitic deficiency

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory