Mouse Genome Informatics
cx
    Abca1tm2Jp/Abca1+
Tg(APOA1)427Bres/?

involves: 129X1/SvJ * C57BL/6J * CBA/J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
homeostasis/metabolism
• moderately reduced total plasma cholesterol
• moderately reduced free cholesterol
• 50% reduction of esterified cholesterol
• moderately reduced HDL cholesterol
• less reduction of phospolipid levels than expected
• less reduction of human apoA-I in plasma than expected

Mouse Models of Human Disease
OMIM IDRef(s)
Tangier Disease; TGD 205400 J:104719