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Phenotypes Associated with This Genotype
Genotype
MGI:3613614
Allelic
Composition		 Mybl2tm1.1Jof/Mybl2tm1.1Jof
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mybl2tm1.1Jof mutation (0 available); any Mybl2 mutation (116 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:103413 )
• fibroblasts isolated from floxed/Mx-Cre mice exhibit cell cycle defects when the cre transgene is induced
• results suggest that this protein is required for S phase and is required for the correct progression of DNA replication

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory