Phenotypes Associated with This Genotype

Genotype
MGI:3613077

• Allelic Composition: Fas^lpr/Fas^lpr
• Genetic Background: MRL/Mp-Agtpbp1^atms Fas^lpr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:103944 )

• body weight is increased by 3 weeks of age in homozygotes that may or may not be heterozygous for atms

enlarged spleen ( J:103944 )

hematopoietic system

enlarged thymus ( J:103944 )

enlarged spleen ( J:103944 )

immune system

enlarged thymus ( J:103944 )

enlarged spleen ( J:103944 )

enlarged lymph nodes ( J:103944 )

• develop lymphadenopathy

neoplasm

increased tumor incidence ( J:103944 )

• develop subcutaneous tumors

integument

ruffled hair ( J:103944 )

• ruffled hair due to superficial prominent lymphadenopathy

endocrine/exocrine glands

enlarged thymus ( J:103944 )