Phenotypes Associated with This Genotype

Genotype
MGI:3611573

• Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Jpmb/Gt(ROSA)26Sor⁺; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: either: (involves: 129S/SvEv * C57BL/6 * CBA) or (involves: 129S/SvEv * C57BL/6 * CBA * CD-1)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

open neural tube ( J:103417 )

• at E9.5 and E10.5, the cranial neural tube is open dorsally

absent midbrain-hindbrain boundary ( J:103417 )

• at E9.5 and E10.5, the isthmus (the constriction of the neural tube at the midbrain hindbrain boundary) is absent

decreased midbrain size ( J:103417 )

• at E9.5 and E10.5 the brain rostral to the otic vesicle is significantly smaller

embryo

open neural tube ( J:103417 )

• at E9.5 and E10.5, the cranial neural tube is open dorsally