Phenotypes for Ikbkb Tnfrsf1a MGI:3609627 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	\Ikbkb^tm1Ver/\Ikbkb^tm1Ver \Tnfrsf1a^tm1Mak/\Tnfrsf1a^tm1Mak
Genetic Background	involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikbkb^tm1Ver mutation (0 available); any Ikbkb mutation (58 available)
Tnfrsf1a^tm1Mak mutation (2 available); any Tnfrsf1a mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:54323 )

• double homozygotes develop to term but die within the first postnatal month, unlike Ikbkb^tm1Ver mutant embryos that die at ~E12.5-E13.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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