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Phenotypes Associated with This Genotype
Genotype
MGI:3609055
Allelic
Composition		 Agttm1Afu/Agttm1Afu
Tg(Fabp4-Agt)2Mte/0
Genetic
Background		 involves: C57BL/6 * CBA * DBA/2 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agttm1Afu mutation (2 available); any Agt mutation (34 available)
Tg(Fabp4-Agt)2Mte mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating angiotensinogen level ( J:73163 )
• plasma angiotensinogen levels are 20-30% of those in wild-type even though transgene expression rescues the Agt mutant phenotype and mutants are normotensive

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory