Phenotypes Associated with This Genotype

Genotype
MGI:3609050

• Allelic Composition: Tg(Fabp4-Agt)2Mte/0
• Genetic Background: involves: C57BL/6 * CD-1 * DBA/2 * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:73163 )

• higher total fat mass, epididymal fat pad weight, and adiposity index than in wild-type

abnormal fat cell morphology ( J:73163 )

• adipocyte hypoplasia

increased fat cell size ( J:73163 )

• increase in cell diameter and weight

increased epididymal fat pad weight ( J:73163 )

• increase in epididymal fat pad weight

cardiovascular system

increased systemic arterial systolic blood pressure ( J:73163 )

growth/size/body

increased body weight ( J:73163 )

• significantly greater body weight than wild-type

homeostasis/metabolism

abnormal blood homeostasis ( J:73163 )

• plasma angiotensinogen levels are increased (from 22 to 44%) compared to wild-type

decreased circulating renin level ( J:73163 )

• lower plasma renin activity

behavior/neurological

decreased locomotor activity ( J:73163 )

• locomotor activity in the daytime is slightly lower than in wild-type