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Phenotypes Associated with This Genotype
Genotype
MGI:3606883
Allelic
Composition
Mc5rtm1Cone/Mc5rtm1Cone
Genetic
Background
B6.129S4-Mc5rtm1Cone
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mc5rtm1Cone mutation (1 available); any Mc5r mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• little or no porphyrin synthesis in response to restraint stress

behavior/neurological
• homozygous males are less aggressive and more defensive when paired with wildtype males, however social and nonsocial behaviors are unaltered and levels of aggression and defense are unaltered when paired with gonadectomized opponents or with other homozygous males
• homozygous males exhibit even less aggression and more defense in the dark phase when paired with wildtype males
• aggressive behavior is not elevated in homozygous males during the dark phase as it is in wildtype


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory