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Phenotypes Associated with This Genotype
Genotype
MGI:3606505
Allelic
Composition		 Glra3tm1Dgen/Glra3tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glra3tm1Dgen mutation (1 available); any Glra3 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased susceptibility to pharmacologically induced seizures ( J:101679 )
• homozygotes require a lower dose of metrazol to induce various seizure stages compared to wild-type mice

nervous system
increased susceptibility to pharmacologically induced seizures ( J:101679 )
• homozygotes require a lower dose of metrazol to induce various seizure stages compared to wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory