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Phenotypes Associated with This Genotype
Genotype
MGI:3604384
Allelic
Composition
Wnt3avt/Wnt3avt
Genetic
Background
involves: C3H/HeJ * C57BL/6J * C57BR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt3avt mutation (1 available); any Wnt3a mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• the most caudal vertebrae have abnormal centers of ossification
• the number of vertebrae with caudal morphology is reduced to 2 - 15 compared to 18 - 25 in heterozygous mice

embryo
• by E11.5, differences in somite number are seen in the caudal region

skeleton
• the most caudal vertebrae have abnormal centers of ossification
• the number of vertebrae with caudal morphology is reduced to 2 - 15 compared to 18 - 25 in heterozygous mice
• the most caudal vertebrae have abnormal centers of ossification


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory