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Phenotypes Associated with This Genotype
Genotype
MGI:3603664
Allelic
Composition		 Men1tm1.2Ctre/Men1+
Tg(Ins2-cre)1Dh/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Men1tm1.2Ctre mutation (1 available); any Men1 mutation (40 available)
Tg(Ins2-cre)1Dh mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased insulinoma incidence ( J:85042 )
• heterozygous mutants develop islet tumors later than homozygous mutants

endocrine/exocrine glands
increased insulinoma incidence ( J:85042 )
• heterozygous mutants develop islet tumors later than homozygous mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory